Clinical reference — what each peptide does, who qualifies, and how it’s dosed.
Peptide & program guide

Understand exactly what you’re taking — and why.

A plain-English guide to every RYNA program: what each peptide does, who can be prescribed it, the age rules, and how it’s dosed. Everything here comes from our clinical program — pricing lives on the main page.

Prescribed only when clinically appropriate Licensed in all 50 states + DC
Eligibility & age rules

Who qualifies — and the age limits

Every prescription is decided by a licensed clinician after a medical evaluation. These are the baseline rules for who can start each program.

Weight loss (GLP-1)

  • Ages 18–74 to start a new program
  • May continue past 74 based on individual evaluation
  • BMI ≥ 27, or ≥ 25 with a related condition

Microdosing

  • Ages 18–74
  • BMI > 20
  • Labs recommended but not required

Sexual health

  • Must be 21 or older
  • Ages 75+: single-ingredient formulas only
  • Prescribed after clinician review

How ingredients change with age: combination (multi-ingredient) sexual-health formulas are available to eligible adults 21–74. At 75 and older, prescriptions are limited to single-ingredient sexual-health medications for safety. GLP-1 programs are started between 18 and 74 and may be continued beyond 74 only after an individual clinical review.

Weight loss & management

GLP-1 medications, explained

GLP-1 medications work with your body’s own appetite signals to reduce hunger, slow digestion, and help your metabolism — so weight comes off steadily and stays manageable. Available as injections or oral (sublingual) forms.

GLP-1

Semaglutide

A single-pathway GLP-1. Curbs appetite and cravings and supports steady weight loss. Available as a weekly injection or a daily oral sublingual (ODT).

Best for

First-time GLP-1 users and those wanting a proven, straightforward path.

GLP-1 / GIP

Tirzepatide

A dual GLP-1/GIP medication that acts on two appetite pathways — often greater appetite control and results. Available as injection or oral sublingual.

Best for

Those seeking maximum appetite control or who’ve plateaued on a single-pathway medication.

Dosing levels

Clinicians titrate you up gradually. Injections are dosed per 4-week cycle; oral sublingual (ODT) is dosed per day. Not everyone reaches the highest level — you move up only as clinically appropriate.

Level Semaglutide inj. / 4 wks Tirzepatide inj. / 4 wks Sema oral ODT / day Tirz oral ODT / day
Level 10.8 mg8.5 mg/cycle5 mg/day3 mg/day
Level 21.6 mg17 mg/cycle10 mg/day6 mg/day
Level 33.2 mg25.5 mg/cycle
Level 45.6 mg34 mg/cycle
Level 58.96 mg44.5 mg/cycle

Personalized compound options

GLP-1s can be compounded to target a specific need alongside weight loss. Your clinician chooses the option that fits you; availability can change and not everyone qualifies for every option.

Option Targets Forms
1Muscle preservation, side-effect supportInjection
2Side-effect support, energy, gradual effectInjection
3Energy, mental acuity, longevityInjection
4Needle aversion / side effects, muscle preservationOral
5Needle aversion, energy, maintenance programOral
6Needle aversion, energy, mental acuity, longevityOral
7Elevated A1C / blood-sugar & hormonal supportOral
8Alcohol reduction / health supportOral
9Smoking cessationOral
10Sleep supportInjection & Oral

Microdosing formulas & ingredients

A gentler, low-dose GLP-1 approach — ideal for maintaining a result you’ve already reached. Each formula blends a microdose of GLP-1 with supportive ingredients.

Muscle & Energy · Oral

GLP-1 + NAD + L-Carnitine + B12

Energy & Mental Acuity · Inject

GLP-1 + NAD + B12

Energy & Mental Acuity · Oral

GLP-1 + NAD + L-Carnitine + B12

Elevated A1C / Prediabetes · Oral

GLP-1 + Inositol

Sleep Support · Oral ODT

GLP-1 + NAD + B12 + Magnesium + L-Theanine

Muscle & Energy + side-effect · Inject / Oral

GLP-1 + B12, Methionine, Inositol, Choline Chloride

Microdosing runs on a 12-week consult rhythm with medication shipped every 4 weeks. Unlimited async & live consults are included; labs are recommended but not required.

Strength, longevity & energy

Peptides for recovery, energy & healthy aging

These programs support how you feel day to day — energy, recovery, sleep, and long-term vitality. Prescribed and monitored by your clinician.

NAD+

Supports cellular energy, mental clarity, and healthy aging. Offered as injection, nasal, or a next-gen oral dropper.

Typical dose

50–200 mg per dose (200mg/ml 5ml vial for injection; 50/100/150mg droppers).

Rhythm

4-week start, then 12-week refills with sync consults on request.

Sermorelin

Supports strength, recovery, sleep quality, and longevity by encouraging the body’s own growth-hormone rhythm.

Typical dose

500–600 mcg per dose (2mg/ml in a 5ml vial for injection).

Rhythm

4-week start, then 12-week refills with sync consults on request.

B12 MIC

A B12 + MIC (methionine, inositol, choline) injection for everyday energy, metabolism, and wellness support.

Form

Injection.

Rhythm

Started on a 12-week prescription, then 12-week refills with sync consults on request.

Sexual health

Formulas & ingredients

Clinician-prescribed combinations, available as single-dose vials or dissolvable ODT/troches. Must be 21+; ages 75+ are eligible for single-ingredient formulas only.

Formula Ingredients Forms
QuattroCompounded sildenafil + tadalafil + vardenafil + apomorphineVial
TriadCompounded sildenafil + tadalafil + vardenafilVial / ODT
IgniteCompounded sildenafil + tadalafil + apomorphineVial / ODT
DuoCompounded sildenafil + tadalafilVial / ODT
EndureCompounded silodosin + tadalafilVial / ODT
DailyCompounded tadalafil, daily (2.5 / 5 mg)Tablet

What each ingredient does

Every formula above is built from these actives. Your clinician chooses the combination and the strength — these describe the role each one plays, not a dose to self-select.

Sildenafil
Fast-acting PDE5 inhibitor

Relaxes the blood vessels of the penis so blood can fill the tissue during arousal. It is the quickest of the group to take effect and the shortest-lived, which is why it anchors the on-demand formulas.

Tadalafil
Long-acting PDE5 inhibitor

Works the same way as sildenafil but stays in the body far longer, giving a wide window rather than a narrow one. At low strength it can also be taken every day, so there is nothing to plan around.

Vardenafil
Selective PDE5 inhibitor

A third PDE5 inhibitor that some men respond to when others fall short. Included in combination formulas to broaden the response rather than to add duration.

Apomorphine
Central dopamine agonist

The only active here that does not work on blood flow. It acts in the brain on the arousal signal itself, so it is added when the difficulty involves desire and initiation rather than circulation alone.

Silodosin
Alpha-blocker

Relaxes smooth muscle in the prostate and bladder neck. In Endure it is paired with tadalafil for men whose sexual concerns overlap with urinary symptoms.

How each formula works in practice

Timing below is typical for these actives and assumes sexual stimulation — none of them produce an erection on their own. Your own timing depends on your dose, your body, and what you have eaten. Your clinician gives you the exact instructions for your prescription.

Formula How you take it Typical onset Typical window Often prescribed when
Quattro
Vial
On demand, ahead of the occasion Roughly 15–30 minutes Into the following day The broadest formula — three PDE5 inhibitors plus the central arousal active, for men who have not responded well to a single ingredient.
Triad
Vial / ODT
On demand; the ODT dissolves in the mouth Roughly 15–30 minutes Into the following day Blood-flow support from three angles, without the central component. A common step up from a single ingredient.
Ignite
Vial / ODT
On demand; the ODT dissolves in the mouth Roughly 15–30 minutes Into the following day Pairs fast and long blood-flow support with apomorphine, when desire and initiation are part of the concern.
Duo
Vial / ODT
On demand Roughly 20–40 minutes Into the following day The straightforward starting combination: a fast active for tonight, a long one for the window after.
Endure
Vial / ODT
On demand or as directed Roughly 30–60 minutes Into the following day Sexual concerns alongside urinary symptoms such as weak stream or frequent night-time trips.
Daily
Tablet, 2.5 / 5 mg
One tablet every day, at the same time Builds over about 5 days of daily use Continuous — no dose to time You would rather not plan around a dose at all, and prefer steady readiness to a single strong occasion.

Never combine these with nitrates, and never take more than one sexual-health formula in the same day. Seek urgent care for an erection lasting more than four hours. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or manufacturing quality. Individual results vary.

Age & ingredient rule: multi-ingredient formulas (Duo, Triad, Ignite, Quattro) are for eligible adults 21–74. At 75+, only single-ingredient sexual-health medications are prescribed.

Always included

What comes with every program

  • Unlimited async & live clinician consults — at no extra cost
  • Labs ordered and paid for (standard Quest/Labcorp panels)
  • Free, discreet medication shipping every 4 weeks
  • 24/7/365 live support from CMAs & RNs
  • GLP-1 patients: optional anti-nausea (ondansetron) support
Your journey

How care actually works

1

Async intake review (or scheduled video visit) — history, labs ordered, initial prescription if appropriate.

2

30-day review of labs & progress; refills as eligible, with live consults whenever you want them.

3

Monthly reviews until steady-state dosing is reached.

4

Quarterly check-ins at steady state; labs typically repeated around 12 months (sooner if clinically indicated).

Optional: Medical Weight-Loss Care Coaching

A supportive, action-oriented coach (Certified Medical Assistant) who builds a personal Care Plan with you — covering side-effect management, nutrition for GLP-1, movement, emotional eating, stress, sleep, and social strategies. Sessions run about every two weeks at your pace, and each ends with easy-to-digest takeaways. It is not dietitian, prescriptive-diet, or mental-health therapy service.

Ready to see which program fits you?

Take the 2-minute quiz — a clinician reviews everything and prescribes only what’s right for you. You pay what you see.

See your price → View all pricing